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Dual smartphone microscopesScientific collaborators from University of California, Los Angeles, Stockholm University, and Uppsala University in Sweden have created a multimodal microscope, that relies on a smartphone’s camera, capable of targeted DNA sequencing and mutation analysis of living tissues. Smartphone microscope 2The microscope consists of a 3D printed component containing a cheap lens that snaps onto a Nokia Lumia 1020, a smartphone that sports a 38 megapixel sensor. Inside the device are two laser diodes that provide multicolor fluorescence imaging and a white LED for bright-field transmission imaging. A sample holder in front of the camera can be moved in three dimensions to place the target spot accurately for optimal imaging. To actually see specific DNA sequences, the team created a fluorescence tagging technique that makes lights up molecular strings being searched for. From the study in Nature Communications: For the molecular analysis, we developed tar...

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At the Ben-Gurion University in Israel researchers have developed a smartphone-based system for evaluating a patient’s obstructive sleep apnea, as well as sleep-wake activity, an analysis of how sleepy one feels. The hope is that this technology, which is easy and cheap to use, may one day serve as an option over traditional polysomnography in some studies. The software uses a smartphone’s microphone to listen to the sounds generated by a sleeping person. These are processed and categorized to identify unique events, such as snoring, coughing, or wheezing. In order to evaluate how accurate their software is, especially since this is certainly not the first attempt at assessing sleep from sounds alone, the researchers conducted a study involving 350 subjects. They found that compared to traditional  traditional polysomnography, their smartphone app was able to accurately identify sleeping events and evaluate obstructive sleep apnea and sleep/wake activity.

UE Lifesciences, a company with offices in the U.S. and India, has developed the iBreastExam, a low-cost point-of-care breast health test for use by community workers in low resource settings. This device is designed to address the rising incidence of breast cancer in developing countries where women have limited or no access to breast cancer screening services. UE Lifesciences have featured on Medgadget previously, for their NoTouch BreastScan, an infrared scanner to detect breast cancer for use in a conventional clinical setting. However, the iBreastExam is their first point-of-care wireless scanner, designed to be highly portable and easy to use. The test is painless and radiation free, and takes less than 5 minutes to complete. The device can be used by any doctor or health worker and the results are available at the point-of-care. iBreastExam assesses differences in tissue elasticity between malignant and non-cancerous breast tissue, and its tactile sensor measures shear stiff...