Protects Wounds, Controls Pain, and Prevents Microbial Infection (Infective Endocarditis)

SockIt! ™ Oral Pain Gel

Protects Wounds, Controls Pain, and Prevents Microbial Infection
(Infective Endocarditis)

There are three main functions of wound dressings: physically protect
the wound, optimize moisture, and prevent microbial infection. The
latter two properties are limited in oral wound dressing due to the
already moist environment and the toxicity of most compounds, that
inhibit microorganism growth, when applied to the oral cavity. Most
of these compounds are synthetic and cause severe damage to already
compromised cells and tissues. SockIt! is composed of 100% natural
food ingredients, so there is no fear of additional damage, and dental
professionals should not be concerned about overgrowth of pathogenic
microorganisms upon application of SockIt!. Furthermore, numerous food
ingredients are natural and effective antimicrobials. Table 1 (below)
illustrates the ability of SockIt! to control microbial growth of
organisms implicated in infective endocarditis in under 30 seconds.

SockIt! Oral Pain Gel is a multi-use product, so it had to undergo
United States Pharmacopoeia (USP) <51> Preservative Challenge Testing.
This test is required by law to ensure the consumer that bacterial
contamination of the production will not occur during the time of use.
Concerns arise with the application of food ingredients to areas of
recently exposed and damaged tissue after a dental procedure because
the components might serve as a food source for opportunistic and/or
pathogenic bacteria implicated in such diseases as: dental caries,
periodontitis, endodontic infections, and infective endocarditis. The
literature was reviewed to identify the most common pathogens
associated with the diseases and we determined the Minimum Inhibitory
Concentration (MIC) and the Time Kill (TK) required to kill and
inhibit the growth of these organisms. The various tables below show
the results of the studies. Table 1 (below) shows the results for the
TK study. The red shading represents time points in which a log
reduction of two or higher was attained, and a log reduction of two
(100 times lower than the initial inoculation level) is considered
"antimicrobial" by the Food and Drug Administration (FDA). Table 2
shows the results for the MIC study, and the red shading denotes the
dilutions that inhibited the growth of the bacteria implicated in
infective endocarditis.

Sockit! is distributed by:

esgdivisionmedica.4t.com