Drug Discovery, Metabolism and Development eNews
Application Note
App Note 436: Bioanalytical Assay for Neurotransmitters in Whole Blood
by LC-MS/MS
An LC-MS/MS method integrating Thermo Scientific TurboFlow technology
with a TLX-1 system for on-line sample extraction is a powerful
technique for the direct analysis of drugs in biological fluids
without the need for lengthy sample preparation.
This combined technology allows for low levels of detection (6.25
ng/mL for C-Dopa; 25 ng/mL for L-Dopa and 3-OMD) of each of the
neurotransmitter compounds in human whole blood extract. Results are
available in less than 10 minutes per sample with the possibility of
attaining results every 2.5 minutes with the use of a Thermo
Scientific Aria TLX-4 multiplexed system.
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Meds, Material & Equipo Médico, 24 hrs.
esgdivisionmedica.4t.com
When the physician receives the EKG results from the technician, he or she will review the patterns recorded by the machine. These patterns may lead to several different diagnoses of heart problems that the machine can pick up, including conduction disorders, electrolyte disturbances, problems with heart valves, and enlarged heart conditions.
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